S
- Southern African National Foundation for The Conservation of Coastal Birds (SANCCOB)
- Southern African Netherlands Chamber of Commerce (SANEC)
- Southern African Plant Breeders’ Association (SAPBA)
- Southern African Plant Breeders’ Association (SAPBA)
- Southern African Plastic Pipe Manufacturers Association (SAPPMA)
- Southern African Project Controls Institute (SAPCI)
- Southern African Pump Systems Development Association (SASPDA)
- Southern African Radiation Protection Association (SARPA-SA)
- Southern African Regional Poverty Network (SARPN)
- Southern African Regional Universities Association (SARUA)
- Southern African Research and Innovation Management Association (SARIMA)
- Southern African Society for Horticultural Sciences (SASHS)
- Southern African Society for Plant Pathology (SASPP)
- Southern African Society for Trenchless Technology (SASTT)
- Southern African Society of Aquatic Scientists (SASAqS)
- Southern African Vehicle Rental and Leasing Association (SAVRALA)
- Southern African Vinyls Association (SAVA)
- Southern African Wildlife Management Association (SAWMA)
- Southern African Wood, Laminate and Flooring Association (SAWLFA)
- Southern African Youth in Energy Sector (SAYES)
- Southern Cape Bee Industry Association (SCBIA)
- Southern Cape Hunters and Conservstion Association (SJB)
- Soutpansberg Chamber of Business and Tourism (SCBT)
- Soweto Independent Shopkeepers Association ()
- Specialty Coffee Association of Southern Africa (SCASA)
- Spectroscopy Society of SA ()
- Speleological Exploration Club (SEC)
- Spinmasters Angling Society (SAS)
- Sport Aerobics and Fitness Federation (SASAFF)
- Sports Science Institute of South Africa (SSISA)