- Social Housing Regulatory Authority (SHRA)
- Society for Animals In Distress (SAD)
- Society for Automation, Instrumentation, Mechatronics and Computer Engineering (SAIMC)
- Society for Endocrinology, Metabolism & Diabetes of South Africa (SEMDSA)
- Society for The Prevention of Cruelty To Animals (Tshwane) (SPCA)
- Society for the Protection of Animals in Africa – South African branch (SPANA)
- Society of Advocates of Kwazulu-Natal (SAKZN)
- Society of Cosmetic Chemists of South Africa (COSCHEM)
- Society of Hearing Aid Acousticians of South Africa (SHAA)
- Society of Master Mariners, South Africa (SOMMSA)
- Society of Maxillo-facial & Oral Surgeons (SAMFOS)
- Society of Medical Laboratory Technology of South Africa (SMLTSA)
- Society of Midwives of South Africa (SOMSA)
- Society of Radiographers of South Africa (SORSA)
- Society of South Africa Geographers (SSAG)
- Society of South African Geographers (SSAG)
- Soil Science Society of SA (SSSSA)
- Soil Science Society of South Africa (SSSSA)
- Solidariteit Helpende Hand (SHH)
- Solidarity Union SA (SUSA)
- Solidarity Union South Africa (SUSA)
- Somerset West Bird Club (SWBC)
- Somerset West Pistol Club (SWPC)
- Sorghum Trust (ST)
- South Africa – Israel Chamber of Commerce (SAICC)
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