C
- Council on Higher Education (CHE)
- Craft Brewers Association South Africa (CBASA)
- Credit Bureau Association (CBA)
- Criminological Association of South Africa (CRIMSA)
- Critical Care Society of South Africa (CCSSA)
- Crop Life South Africa (CLSA)
- Crossroads Chess Club (CCC)
- Cuckoo Bird Club (CBC)
- Culture, Arts, Tourism, Hospitality and Sport Education and Training Authority (CathsSETA)
- Cycad Society of South Africa (CSSA)
- Cycling South Africa (CSA)
- Cyril Ramaphosa Foundation (CRF)
- The Colleges of Medicine of South Africa (CMSA)
- The Compassionate Friends (TCF)