S
- Society for the Advancement of Physics and Engineering (SAPE)
- Society for The Prevention of Cruelty To Animals (Tshwane) (SPCA)
- Society of Advocates of Kwazulu-Natal (SAKZN)
- Society of Cosmetic Chemists of SA (COSCHEM)
- Society of Dispensing Family Practitioners (SDFP)
- Society of Hearing Aid Acousticians of SA (SHAA)
- Society of Master Mariners, SA (SMMSA)
- Society of Maxillo-facial & Oral Surgeons (SAMFOS)
- Society of Medical Laboratory Technology of SA (SMLTSA)
- Society of Midwives of SA (SOMSA)
- Society of Psychiatrists of SA (SASOP)
- Society of Radiographers of SA (SORSA)
- Society of SA Geographers (SSAG)
- Soil Science Society of SA (SSSSA)
- Solidariteit Helpende Hand (SHH)
- Solidarity Union SA (SUSA)
- Somerset West Bird Club (SWBC)
- Somerset West Pistol Club (SWPC)
- Sorghum Trust (ST)
- South Africa – Israel Chamber of Commerce (SAICC)
- South Africa Guernsey Cattle Breeders Society (SAGCBS)
- South African Garage Door Association (SAGDA)
- South African Institute of Taxation (SAIT)
- South African Abalone Export Council (SAAEC)
- South African Academy of Aesthetic Dentistry (SAAAD)
- South African Academy of Engineering (SAAE)
- South African Academy of Family Physicians (SAAFP)
- South African Advertising Research Foundation (SAARF)
- South African Aerospace Maritime and Defence Export Council (SAAMDEC)
- South African Affordable Residential Developers Association (SAARDA)